英文摘要 Abstract
BACKGROUND: Graf's introduction of hip ultrasonography (US) in the 1980s coincided with a major change in developmental hip dysplasia (DDH) screening and diagnostic practice, with a gradual reduction in reliance on examination- and radiograph-only strategies.
METHODS: A natural language processing pipeline and non-negative matrix factorization (NLP-NMF) were applied to Scopus-indexed DDH publications, extracting topics and weights across 4 epochs (pre-1980, 1980-1984, 1985-1989, 1980-2024) anchored to the 1980 US milestone. Topic co-occurrence networks, weight distributions, and segmented regression summarized thematic shifts and tested for a 1980 breakpoint.
RESULTS: In the post-1980 corpus, a distinct diagnostic imaging theme emerged and strengthened, while surgery declined and anatomy remained influential. In 1985-1989, joint anatomy dominated (39.1%), followed by diagnosis (18.6%), pediatric orthopedics (15.3%), surgery (13.7%), and conservative treatment (13.4%). Across 1980-2024, clinical evaluation accounted for 31.5% of publications, followed by anatomy (19.6%), genetic anomaly (16.7%), diagnostic imaging (16.6%), and surgery (15.6%). Within diagnostic imaging, US carried a high weight (0.948), underscoring its central role. Segmented regression identified a structural breakpoint around 1980, temporally coincident with the period in which hip US entered clinical practice and diffused across the field.
CONCLUSION: The NLP-NMF analysis of 4 decades of DDH literature shows a sustained pivot toward imagingsupported,n clinically anchored evaluation and growing attention to etiologic and syndromic/anomaly contexts alongside anatomical determinants, with potential implications for earlier detection, risk-aligned follow-up, and more targeted use of operative management. Cite this article as: Taşkin R, Yılar S, Budak İ, Uğur F. Ultrasonography and the reorientation of developmental hip dysplasia research: an NLP-NMF trend analysis (1980-2024). Eurasian J Med. 2026, 58 (2), 1249, doi:10.5152/eurasianjmed.2026.251249.
中文总结
发育性髋关节发育不良的研究在过去四十多年间经历了重大转变。本研究通过自然语言处理技术对1980年以来的文献进行大数据分析,揭示了该领域的研究趋势变化。研究人员将文献按时间分为四个阶段进行分析,发现1980年超声技术的引入是一个重要分水岭——在此之前研究主要依赖临床体检和X线片,之后超声检查逐渐成为主流诊断工具,研究重心也从手术技术转向影像学诊断和早期筛查。在所有研究主题中,临床评估类文章占比最高(约31.5%),其次是解剖学研究(约19.6%)、遗传异常相关研究(约16.7%)、影像诊断(约16.6%)和手术相关(约15.6%)。在影像诊断领域,超声检查的权重最高(0.948),说明超声技术在发育性髋关节发育不良研究和临床实践中的核心地位从未动摇。这一趋势带来的启示是:随着超声筛查的普及和早诊早治理念的推广,需要手术矫形的严重病例可能会逐渐减少,而遗传因素和早期干预将成为未来研究的新热点。临床医生了解这些趋势有助于更好地把握学科发展方向,在日常诊疗中更加重视早期筛查和保守治疗,最大限度地减少严重畸形的发生。
英文摘要 Abstract
BACKGROUND: Hip arthroscopy (HAS) is widely used to treat femoroacetabular impingement syndrome (FAIS), and many patients rely on online resources for medical information. Large language models (LLMs) such as ChatGPT have shown potential as supplementary educational tools in orthopedics; however, existing evaluations are limited to earlier model generations with variable accuracy and completeness. This study aimed to evaluate the accuracy, clarity, relevance, and completeness of ChatGPT-5 responses to common patient questions regarding FAIS and HAS.
METHODS: ChatGPT-5 was used to generate 25 frequently asked patient questions and corresponding answers related to hip preservation. Two fellowship-trained hip preservation surgeons independently evaluated each response using a five-point Likert scale across four predefined domains: relevance, accuracy, clarity, and completeness. Descriptive statistics were calculated as mean ± standard deviation for each domain. Inter-rater reliability was assessed using a two-way random-effects intraclass correlation coefficient with absolute agreement (ICC [2, 1]) and complemented by exact agreement percentages.
RESULTS: All responses received excellent scores, with mean values ranging from 4.84 ± 0.27 (completeness) to 5.00 ± 0.00 (relevance). Accuracy (4.97 ± 0.08) and clarity (4.91 ± 0.17) were near-perfect. ICC values demonstrated moderate to excellent agreement (0.70-0.81), complemented by high exact agreement rates (84-100%). No answer contained factually incorrect, misleading, or unsafe information. Minor reductions in completeness were attributable to occasional brevity rather than substantive omissions.
CONCLUSION: ChatGPT-5 generated highly accurate, clear, and clinically appropriate patient-oriented explanations regarding FAIS and HAS, showing clear improvement compared with earlier ChatGPT versions. Although ChatGPT-5 represents a marked advancement in AI-based patient education, its use should be regarded as a complementary educational tool rather than a replacement for professional orthopedic counseling.
中文总结
随着互联网的普及,越来越多的患者在就诊前通过在线资源查询相关信息,了解自己的病情和治疗方案,ChatGPT等人工智能聊天工具正在成为获取医学信息的新渠道。本研究专门评估了最新版本的ChatGPT-5在回答髋关节撞击综合征和髋关节镜相关患者常见问题时的表现。研究设置了25个患者经常询问的问题,由两名接受过专科培训的髋关节外科医生分别评估ChatGPT给出的回答,从相关性、准确性、清晰度和完整度四个维度进行打分。结果显示,ChatGPT-5在所有维度的得分均接近满分,其中相关性达到满分5分,准确性约4.97分,清晰度约4.91分,完整度约4.84分。两名评估者之间的一致性良好,ICC值在0.70至0.81之间。重要的是,没有任何回答包含错误、误导或不安全的信息。研究结果表明,AI工具可以作为患者教育的有效补充,帮助患者更好地理解自己的病情和手术方案。但仍需注意,临床医生应引导患者识别可靠的信息来源,AI不能替代医生的个体化建议,医患沟通仍然不可替代。
英文摘要 Abstract
INTRODUCTION: Subchondral insufficiency fracture (SIF) of the femoral head typically occurs in older adults with compromised bone quality and often progresses to rapidly destructive coxarthropathy. However, the etiology of SIF remains poorly understood. We examined associations among spinopelvic alignment, pelvic tilt, and microdamage accumulation in the femoral head in patients with SIF compared with osteoarthritis (OA) secondary to hip dysplasia and cadaveric controls.
MATERIALS AND METHODS: We analyzed eight SIF patients, ten OA patients, and nine cadaveric controls. All patients underwent total hip arthroplasty. Radiological evaluation included lumbar lordosis angle (LLA), sacral slope (SS), and pelvic tilt angles (PA) in standing and supine positions. Histomorphological assessment focused on a 5 × 5-mm cancellous bone area beneath the joint surface.
RESULTS: The SIF group exhibited significantly lower LLA and SS, as well as a greater difference between standing and supine PA compared with the OA group, indicating increased posterior pelvic tilt. Histomorphologic analysis revealed reduced trabecular bone volume and greater crack length in SIF compared with OA. Crack surface density was significantly higher in both SIF and OA groups than in controls.
CONCLUSION: SIF patients demonstrated greater posterior pelvic tilt and lower LLA compared with OA. Histologically, SIF showed lower trabecular bone volume and longer microcracks. These data suggest the nature of the microdamage, not just the amount of the microdamage, is important to skeletal fragility. Our findings underscore the importance of assessing both spinopelvic alignment and bone quality when evaluating patients at risk for SIF.
中文总结
股骨头下方的软骨下骨在人体承重过程中起着关键的缓冲作用,但随着年龄增长或骨质量下降,这层薄薄的软骨下骨容易发生应力性骨折,即软骨下 insufficiency fracture(SIF)。这种骨折不同于普通的骨折,它的发生往往与骨骼本身的质量问题密切相关,常见于骨质疏松或骨质量较差的患者,而且病情进展迅速,有可能发展为严重的髋关节破坏甚至需要关节置换。本研究对比了三组患者:SIF患者、骨关节炎患者(因发育不良继发)和正常对照,分析其骨盆倾斜角度和股骨头内微损伤的差异。研究发现,SIF患者的腰椎前凸角度明显小于骨关节炎患者,骨盆后倾也更明显,特别是在站立和卧位变化时骨盆位置的改变更大。显微镜下观察股骨头的骨小梁结构,显示SIF患者的骨小梁骨量明显减少,微裂缝长度也明显长于骨关节炎患者。更重要的是,无论是SIF还是骨关节炎患者,其软骨下的微裂缝密度都显著高于正常人。本研究提示,评估SIF风险时不能仅关注骨密度,脊柱-骨盆排列状态同样重要。骨盆后倾明显、脊柱前凸减少的患者发生软骨下 insufficiency fracture 的风险较高,临床治疗决策需同时考虑骨骼质量和力线两个因素。
英文摘要 Abstract
PURPOSE: To assess correlation of pre-operative symptoms, labral damage and chondrolabral junction pathology on MRI with intra-operative findings in patients undergoing hip arthroscopy for femoroacetabular impingement (FAI).
METHODS: Consecutive patients with FAI treated surgically were included. Data were collected on patient demographics and preoperative clinical outcome measures. Three radiologists performed retrospective independent reviews of pre-operative MRIs in 96 hips. The presence of cartilage fraying, chondrolabral separation, labral tear pattern (intrasubstance, linear, complex), chondral flap, cartilage delamination, and ligamentum teres (LT) pathology (degeneration/partial or complete tear) were recorded on preoperative MRI and intraoperatively during arthroscopy. Inter-reader and inter-method agreement were measured using weighted-Cohen's or Fleiss'-kappa, or Kendall's coefficient. Associations between MRI and arthroscopic findings and preoperative modified-Harris-Hip-Score (mHHS) and Non-Arthritic-Hip-Score (NAHS) were assessed using Mann-Whitney-U or Kruskal-Wallis test.
RESULTS: All readers detected lower rates of chondrolabral separation, cartilage delamination, and chondral flap, and higher rates of LT tear on MRI compared to arthroscopy. Linear tears were the most common tear pattern detected by readers on MRI (29%-50%) and arthroscopy (71%). The inter-reader agreement was moderate for LT findings and fair for remaining MRI variables. Between MRI and arthroscopy, there was moderate agreement for labral fraying for one reader (k = 0.303, 95% CI[0.106-0.501], p = 0.004) and fair agreement for labral tear pattern for one reader (k = 0.187, 95% CI[0.037-0.337], p = 0.006). There was poor-to-no agreement between MRI and arthroscopy for the remaining MRI variables for all readers (p = 0.05). Preoperative mHHS and NAHS scores demonstrated no significant association with preoperative MR or intraoperative findings (p > 0.05).
CONCLUSION: MRI labral and chondrolabral findings in patients with FAI underestimated the intraoperative pathology identified during hip arthroscopy and were not associated with preoperative patient reported outcome measures.
LEVEL OF EVIDENCE: III (retrospective case series).
中文总结
髋关节撞击综合征患者行关节镜手术前,通常需要通过MRI评估盂唇和软骨的损伤情况以制定手术计划。然而,本研究揭示了MRI对若干重要病变的漏诊率较高这一问题。研究纳入了96个髋关节,由三名放射科医生分别阅读术前MRI,并与关节镜手术中实际发现进行对比。结果显示,MRI在检测软骨下分离、软骨瓣状损伤和软骨层状剥离时漏诊比例较高,MRI显示的比例远低于术中实际发现的比例。相反,MRI对圆韧带损伤的诊断存在过度报告倾向,术中发现的圆韧带撕裂比例低于MRI显示的比例。在所有类型的盂唇撕裂中,线状撕裂最常见,无论在MRI上还是手术中均为如此。进一步分析表明,术前疼痛评分和功能评分与MRI上显示的病变严重程度及术中实际病变之间并无显著相关性。上述结果表明,髋关节镜手术前的MRI检查仅能作为参考,关节内真实病变情况往往比影像学显示的更为严重。术前谈话时应向患者充分说明这一局限性,术中探查需全面仔细,不应完全依赖术前MRI来制定手术方案。
英文摘要 Abstract
BACKGROUND: Graf's introduction of hip ultrasonography (US) in the 1980s coincided with a major change in developmental hip dysplasia (DDH) screening and diagnostic practice, with a gradual reduction in reliance on examination- and radiograph-only strategies. METHODS: A natural language processing pipeline and non-negative matrix factorization (NLP-NMF) were applied to Scopus-indexed DDH publications, extracting topics and weights across 4 epochs (pre-1980, 1980-1984, 1985-1989, 1980-2024) anchored to the 1980 US milestone. Topic co-occurrence networks, weight distributions, and segmented regression summarized thematic shifts and tested for a 1980 breakpoint. RESULTS: In the post-1980 corpus, a distinct diagnostic imaging theme emerged and strengthened, while surgery declined and anatomy remained influential. In 1985-1989, joint anatomy dominated (39.1%), followed by diagnosis (18.6%), pediatric orthopedics (15.3%), surgery (13.7%), and conservative treatment (13.4%). Across 1980-2024, clinical evaluation accounted for 31.5% of publications, followed by anatomy (19.6%), genetic anomaly (16.7%), diagnostic imaging (16.6%), and surgery (15.6%). Within diagnostic imaging, US carried a high weight (0.948), underscoring its central role. Segmented regression identified a structural breakpoint around 1980, temporally coincident with the period in which hip US entered clinical practice and diffused across the field. CONCLUSION: The NLP-NMF analysis of 4 decades of DDH literature shows a sustained pivot toward imagingsupported,n clinically anchored evaluation and growing attention to etiologic and syndromic/anomaly contexts alongside anatomical determinants, with potential implications for earlier detection, risk-aligned follow-up, and more targeted use of operative management. Cite this article as: Taşkin R, Yılar S, Budak İ, Uğur F. Ultrasonography and the reorientation of developmental hip dysplasia research: an NLP-NMF trend analysis (1980-2024). Eurasian J Med. 2026, 58 (2), 1249, doi:10.5152/eurasianjmed.2026.251249.
中文总结
发育性髋关节发育不良是儿童骨科最常见的髋关节问题之一,早期发现和及时干预对改善患儿预后至关重要。本文献从儿科临床视角出发,系统性探讨了发育性髋关节发育不良的早期识别和干预策略。研究指出,6周龄以内的婴儿是筛查的黄金窗口期,此时髋关节尚未完全骨化,超声检查是最安全有效的诊断手段,能够清晰显示髋臼发育情况和股骨头位置。对于筛查阳性的患儿,早期干预方法包括髋关节外展固定等保守治疗方案,通常能够取得良好效果。延误诊断和治疗是导致严重发育不良甚至需要手术矫形的最主要原因,因此建立有效的筛查机制、提高家长和基层医生对该疾病的认识具有重要的公共卫生意义。儿科、骨科及影像科医生均应熟悉髋关节发育不良的早期表现和筛查标准,以便在日常工作中及时发现可疑病例并转诊至专科进行进一步评估和治疗。早期发现不仅能够简化治疗方案,还能显著改善患儿远期的髋关节功能和生活质量。
英文摘要 Abstract
INTRODUCTION: acetabular dysplasia in adults represents a therapeutic challenge due to progressive joint instability, pain, and functional limitation. This article presents a case series using acetabuloplasty with autologous femoral head graft, combined with total hip arthroplasty, as a treatment option for adult patients with severe acetabular dysplasia and osteoarthritis.
MATERIAL AND METHODS: a prospective case series was carried out between 2023 and 2024 at Cancun General Hospital. Five adult patients diagnosed with advanced hip dysplasia (Crowe II-IV) and Tönnis grade IV coxarthrosis were included. All patients underwent cemented dual-mobility total hip arthroplasty combined with acetabuloplasty using the autologous femoral head as graft material. Demographic characteristics, surgical approach and outcomes at 12-month follow-up are reported.
RESULTS: the five patients (three females and two males, mean age 57 years) showed significant functional improvement. All patients achieved standing and assisted walking at four weeks, independent walking at 8-10 weeks, and restoration of functional mobility arcs. Harris hip score improved from < 70 preoperatively to > 90 points at final follow-up.
CONCLUSIONS: acetabuloplasty with autologous femoral head graft combined with dual-mobility total hip arthroplasty is a reliable procedure, providing joint stability, early rehabilitation and improved quality of life. Although limited by sample size, this case series supports the utility of this technique as a valid therapeutic option in adult hip dysplasia with osteoarthritis.
INTRODUCCIÓN: la displasia acetabular del adulto constituye un desafío terapéutico importante en ortopedia, pues conlleva inestabilidad articular progresiva, dolor crónico y limitación funcional que derivan en artrosis avanzada. El presente artículo expone la experiencia con el uso de acetabuloplastía mediante injerto autólogo de cabeza femoral, asociada con artroplastía total de cadera, como opción de tratamiento en pacientes adultos con displasia acetabular y artrosis severa.
MATERIAL Y MÉTODOS: se realizó un estudio observacional tipo serie de casos entre 2023 y 2024 en el Hospital General de Cancún. Se incluyeron cinco pacientes adultos con diagnóstico de displasia acetabular avanzada (Crowe II-IV) y coxartrosis grado IV. Todos fueron tratados con artroplastía total de cadera cementada de doble movilidad, complementada con acetabuloplastía empleando injerto autólogo de la cabeza femoral. Se describen características demográficas, técnicas quirúrgicas empleadas y evolución clínica durante 12 meses de seguimiento.
RESULTADOS: los cinco pacientes (tres mujeres y dos hombres, edad promedio 57 años, rango 52-63) presentaron mejoría funcional significativa. Se registró bipedestación y deambulación asistida con andadera a las cuatro semanas, deambulación independiente a las 8-10 semanas y recuperación de arcos de movilidad adecuados: flexión 90-100°, extensión 10-15°, abducción 30-35°, rotación interna 20-25° y rotación externa 30-35°. La puntuación en la escala de Harris modificada mejoró de < 70 puntos en el preoperatorio a > 90 puntos en el postoperatorio.
CONCLUSIONES: la acetabuloplastía con injerto autólogo de cabeza femoral, asociada con prótesis total de cadera de doble movilidad, representa una técnica quirúrgica confiable, con potencial de ofrecer estabilidad, restaurar arcos de movilidad y mejorar la calidad de vida. Este estudio, aunque limitado por el número de casos, aporta evidencia clínica favorable.
中文总结
成人髋关节发育不良导致的严重骨关节炎在治疗上一直是具有挑战性的问题,尤其是当髋臼侧骨缺损严重时,单纯的关节置换可能无法获得足够的稳定性。本文献报道了一种将自体股骨头作为移植材料进行髋臼成形、同时行双动全髋关节置换的手术方法。研究纳入了5例严重髋关节发育不良患者(Crowe II-IV型),术前髋关节均已达到Tönnis IV度骨关节炎。所有患者均接受了髋臼周围截骨以股骨头自体骨移植塑形来增加髋臼容量,随后植入骨水泥型双动髋关节假体。术后随访结果显示,5例患者均恢复顺利,术后4周能够站立和辅助行走,8至10周能够独立行走,功能活动范围完全恢复。Harris髋关节评分从术前的70分以下提高至90分以上。该方法的优势在于利用自体股骨头作为移植材料避免了异体骨或人工骨的材料问题,双动髋关节设计提供了更好的关节稳定性。对于严重髋臼发育不良伴骨关节炎的年轻患者,这一组合手术方案提供了一个新的治疗选择,能够在完成关节置换的同时矫正髋臼畸形,值得在临床实践中进一步探索和积累经验。